That level of fanfare was nowhere to be found on Thursday, when the company added another $120 million to its coffers and quietly changed its name to Biosplice Therapeutics. Biosplice Therapeutics. Learn More. The program with Bristol Myers Squibb is targeting STAT3. The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. Pretzel Therapeutics Launches with $72M to Advance Mitochondrial . Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). Out of these 85 have been granted leading to a grant rate of 98.8%. DUBLIN, Feb. 28, 2023 /PRNewswire/ -- The "Osteoarthritis Market Size and Trend Report including Epidemiology and Pipeline Analysis, Competitor Assessment, Unmet Needs, Clinical Trial Strategies . Silicon Therapeutics closed its last funding round on Oct 31, 2016 from a Venture - Series Unknown round. Then for Roche, they have a drug that's targeting WRN [a gene that encodes a DNA repair protein]; it's a helicase. Other companies have tried this with limited success, but Candel's phase 2 data looks promising. Biosplice Therapeutics is a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases. Gerostate Alpha raising $500k through WeFunder (Live Now). Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, . When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. All trademarks, logos and company names are the property of their respective owners. Registering gives you access to one of our Private Market Specialists who can guide you through the process of buying or selling. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. The company's claim to fame is that it's amassed a huge library of compounds, and it has a screening technology to help it find the needles in the haystack. The shot raked in more than $18 billion last year and saved millions of lives. Ikena has entered into a global strategic collaboration with Bristol Myers Squibb on the IK-175 and IK-412 programs. Integrating digital therapeutics early in the asset development process will allow for gathering of clinical data to drive a clearer value proposition that maximizes the potential of both products Catherine Stehman-Breen, Chroma Medicine CEO, David Ricks, Eli Lilly CEO (David Paul Morris/Bloomberg via Getty Images), Hemolytic Anemia Sales Specialist, Rare Genetic Diseases, Osman Kibar lays down his hand at Samumed, stepping away from CEO role as his once-heralded anti-aging biotech rebrands, Digital therapeutics: The key to maximizing the potential of medicinal assets, A radioactive prostate cancer therapy is a last lifeline for patients. They have two partners at Bristol Myers Squibb ( BMY -1.71%) and Roche [Holding] ( RHHBY -2.31%). Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. Contacts. Learn more about Biosplice Therapeutics stock Updated on: Jun 12, 2022 Register for Details Investing in private companies may be considered highly speculative and involves a high degree of risk, including the risk of substantial loss of investment. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. Biosplice Therapeutics is funded by 11 investors. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. Ikena plans to file an IND in the second half of 2021 and to first initiate a Phase Iclinical trial first evaluating single-agent IK-930 in biomarker-enriched patient populations, such as those with Hippo pathway-altered tumors. The data in the chart above is based on data derived from our proprietary XP calculation model and may be changed, adjusted and updated without prior notice. The Motley Fool has a disclosure policy. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. Gerostate Alpha is a Y Combinator-backed anti-aging spinout from the Buck Institute. Biosplice contact info: Phone number: (858) 926-2900 Website: www.biosplice.com What does Biosplice do? The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. Jan 2017 - Mar 20225 years 3 months. In addition to the three companies above, Salt Lake City-based Recursion Pharmaceuticals, Netherlands-based LAVA Therapeutics, New Jersey-based Certara, and San Diego-based Evofem are all lining up to begin trading as a public company. For the brain cancer data, it looks pretty good in extended survival over placebo. This week began with four biopharma companies announcing intentions to become publicly traded companies and its ending with three companies making their debut on the Nasdaq. They say they will not only cure arthritis, but also cancer in the future with their amazing technology. Alfredo Naj Domingos prostate cancer was spreading. Tom Jones take zinc after sex or personal release. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Boston-based Ikena said it expects to raise $125 million from the IPO. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to. Learn more about Biosplice Therapeutics stock. Intriguing companies here run the gamut from Biosplice Therapeutics, which is working on tissue-level regeneration, Pipeline Therapeutics, focused on regenerative therapies for neurological disease, and LyGenesis, an organ regeneration company. Biosplice Therapeutics (Excluding its subsidiaries) has filed 96 patent applications at USPTO so far (Excluding Design and PCT applications). Biosplice Therapeutics was founded in 2021. Copyright 2023 Forge Global, Inc. All rights reserved. His wife, Nora Flor, said she and her sister made calls to at least 30 centers across the US looking for the drug. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. X0002 is . Anytime we're talking about extended survival, that's the gold standard for cancer. Biosplice Therapeutics is a private company and not publicly traded. Each of these companies announced their intentions this week. Please note the magic link is SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Please note this link is one-time use only and is valid for only 24 hours. Biosplices target class governs the selection of tissue-specific mRNA splice sites, making them attractive, druggable targets within the cellular command and control center. Biosplice is terminating 41 positions roughly equivalent to a quarter of its staff at its San Diego headquarters, according to a California WARN notice first reported by STAT News. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to other degenerative conditions. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. . Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Biosplice Therapeutics, Inc. ClinicalTrials.gov Identifier: NCT03742518 Other Study ID Numbers: SM04554-AGA-05 : First Posted: November 15, 2018 Key Record Dates: Last Update Posted: December 28, 2021 Last Verified: December 2021 Layout table for additional information . Biosplice Therapeutics has produced fresh biological insights and unique chemical equity that delivers therapeutic modulation of alternative splicing by targeting the CLK/DYRK family kinases. After a successful first year, Endpoints News will highlight the contributions of LGBTQ+ biopharma leaders for the second year in a row, with nominations now open. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. Conversely, dysregulated alternative splicing can be a root cause of developmental disorders, tissue degeneration and cancer. Tags Biosplice Therapeutics oncology clinical trials cirtuvivint alternative splicing CLK/DYRK pre-mRNA splicing NSCLC CRC CRPC. The information provided on Xipometer.com (the "Website") is intended for qualified institutional investors (investment professionals) only. EquityZen Securities LLC (EquityZen Securities) is a subsidiary of EquityZen Inc. EquityZen Securities is a broker/dealer registered with the Securities Exchange Commission and is a FINRA/SIPC member firm. Boulder, Colo.-based Edgewise Therapeutics will also begin selling its common stock this morning on the Nasdaq under the ticker symbol EWTX. The stock will begin trading at $16 per share and are expected to net the company about $176 million from the IPO. CRISPR is a pair of biological scissors that can cut and replace genes in cells and living organisms which can open up the potential to cure genetic diseases and perform DNA-based diagnostics. Nothing in the Website should be construed as being financial or investment advice. You can also learn more about how to sell your private shares before getting started. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200, GLOBAL MARKETS-US stocks muted, Treasuries dip as inflation worries linger, Stock market news today: Stocks waver after key manufacturing data, Salesforce set to report earnings Thursday, Goldman Sachs tries to reset firm culture after three 'unusual' years, Shipping companies reach $97M California oil spill agreement. Content on the Website is provided for informational purposes only. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. . Please note the magic link is magic link that lets you log in quickly without using a password. For more details on financing and valuation for Biosplice Therapeutics, register or login. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. 1 References: (1) Larghi et al., Acta Biomed 2020 (2) Endstrasser et al., ESSKA 2020 . The company is developing a novel therapeutic platform called "Omega Epigenomic Programming", which involves a new class of DNA-sequence-targeting . Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. Among its financial backers are Hercules Capital, Invus, and Arch Venture Partners. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. Biosplice Therapeutics (formerly Samumed) "Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing.". Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. Biosplice Therapeutics is attempting to clear its late-stage knee osteoarthritis treatment after other biopharmas have reached snags in the past year, and it now has $140 million worth of confidenc Eli Lilly is looking to get ahead of any more federal action on insulin prices, announcing today that it will not only slash its most commonly used insulin by 70%, but cap out-of-pocket costs for those on commercial insurance at $35 per month just as the federal government recently did for those insured by Medicare. Amicus Therapeutics began March with word that the FDA has scheduled a pre-approval inspection of its potential treatment for Pompe disease. The company is headquartered in San Diego, California. Unlock this article along with other benefits by subscribing to one of our paid plans. Michael White, Ph.D. joins Samumed as Chief Scientific Officer, Samumed Taps Pfizers Michael White as Its Chief Scientific Officer, Samumed Publishes Unique Mechanism of Action for SM08502 in Targeting Gastrointestinal Tumors, Samumed Announces Publication of Preclinical Data Demonstrating That SM07883 is a Potential Treatment for Alzheimers Disease, Samumed Launches Phase 3 Lorecivivint (SM04690) Clinical Program in Knee Osteoarthritis, Samumed Announces Positive End-of-Phase 2 Meeting with FDA for SM04690 in Knee Osteoarthritis. Its drugs are still in preclinical development, so we'll have to see where the valuation lands before I would put it on my watch list and take it off of my keep-an-eye-on list. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. David Ricks, Eli Lilly CEO (David Paul Morris/Bloomberg via Getty Images), Catherine Stehman-Breen, Chroma Medicine CEO, Alex Denner (Mark Neuling/CNBC/NBCU Photo Bank via Getty Images), Hemolytic Anemia Sales Specialist, Rare Genetic Diseases, Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace, Digital therapeutics: The key to maximizing the potential of medicinal assets, A radioactive prostate cancer therapy is a last lifeline for patients. The Motley Fool owns shares of and recommends Bristol Myers Squibb. Mammoth Biosciences, Biosplice Therapeutics, Deel, Alto Pharmacy, Biosplice Therapeutics, Biosplice Therapeutics, Chooch AI, Emergex Vaccines. It might be worth that much, but on a risk-adjusted basis, I just don't know. The stick will trade under the ticker symbol IKNA.. Novartis can't make enough of it, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, Cell therapy biotech from Stanford CAR-T leader Crystal Mackall nabs $200M for PhII, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Keytruda hits one primary endpoint for use before and after surgery in lung cancer, Amicus eyes Pompe approval; Atea ends Dengue work; 2seventy, Travere line up offerings. The move to again slash the cost of insulin back in 2019, Lilly cut the list price of Humalog by 50% comes as rationing of the life-saving shot has led to deaths for some diabetics who could not afford their injections, even as Congress is working on another push to cap out-of-pocket costs for diabetics after Senate Republicans shot down the idea last August. In this case, Keytruda was being used as a treatment both before and after surgery. About. Investors must be able to afford the loss of their entire investment. To make the world smarter, happier, and richer. Focused on tissue-level regeneration to treat aging related diseases, Biosplice states its mission is to "restore human health via novel therapies that use alternative splicing Fulcrum Therapeutics Announces Clinical Hold on FTX-6058 in Sickle Cell Disease,CAMBRIDGE, Mass., Feb. 24, 2023 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on. 308 followers 310 connections. In this Motley Fool Live video recorded on June 30, 2021, Motley Fool contributors Keith Speights and Brian Orelli discuss two upcoming biotech stock IPOs you'll want to have on your radar. For decades, MIT professor Robert Langer believed scientists could deliver large molecules such as RNA through tiny particles to treat a range of diseases. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. Brian, are there any of these that you think investors should want to have on their radar? Price as of February 28, 2023, 4:00 p.m. On our trusted digital marketplace for private companies. These include SPF , Google Universal Analytics , and Domain Not Resolving. When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data The approval request includes both a BLA and NDA. EDG-5506 is currently being assessed in a Phase I study. Ikena Oncology, a company focused on developing cancer therapies targeting key signaling pathways that drive the formation and spread of cancer, begins trading on the Nasdaq at $16 per share. The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, and . Now, the biotech is laying off a large swath of its staff as it undergoes a pipeline overhaul. Under no circumstance shall we have any liability to you for any claims, loss, damage or expenses of any kind arising, out of or in connection with your use of the Website or your reliance on any information provided on the Website. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. By Alex Keown. Already registered? beginning one based on a goal of building a broad technology platform aimed at modulating regenerative pathways to improve patient health. Learn more about how to invest in the private market or register today to get started. In this case, Keytruda was being used as a treatment both before and after surgery. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases,. Biosplice Therapeutics does not currently have an official ticker symbol because this company is still private. Register today to connect with our Private Market Specialists and learn more about new pre-IPO investment opportunities. *Stock Advisor returns as of June 7, 2021. Notable lists of unicorn companies are maintained by The Wall Street Journal, Fortune Magazine, CNNMoney/CB Insights, TechCrunch, PitchBook/Morningstar, and Tech in Asia. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. Biosplice Therapeutics's latest funding round was a Series B for $120M on April 15, 2021. Alfredo Naj Domingos prostate cancer was spreading. Some like Sana Biotechnology (SANA -0.81%) are still in preclinical. The company started in 2015 and is . At least those big pharma partners have looked at the early-stage preclinical data. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. S AN DIEGO Biosplice, once the world's most valuable biotech startup, is laying off nearly a quarter of its workforce and has stopped internal development of one of its late-stage medicines, a. Learn more at https://www.biosplice.com. Gene therapy, precision medicine and genome analysis "Mr. Johnson's vast experience ushering drugs from . Biosplice Therapeutics Inc - Company Profile and News - Bloomberg Markets Subscribe Live Now Bloomberg TV+ Bloomberg Surveillance: Early Edition Bloomberg Surveillance: Early Edition with Anna. Biosplice Therapeutics, Inc. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders, today reported financial results for the fourth quarter and full year ended December 31, 2022. His wife, Nora Flor, said she and her sister made calls to at least 30 centers across the US looking for the drug. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for . Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation Merck has been looking to get its blockbuster drug Keytruda into earlier lines of treatment, and one of its latest trial results has the anti-PD-1 antibody moving firmly in that direction. If you're already an Endpoints subscriber, enter your email below for a By accessing this site and any pages thereof, you agree to be bound by our Terms of Use.EquityZen and logo are trademarks of EquityZen Inc. Other trademarks are property of their respective owners. 2023 EquityZen Inc. All rights reserved. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. If you are interested in buying or selling private company shares, you can register with Forge today for free to explore your options. CIOs and business technology executives at this event will also discuss how men Shanghai Everest Medicines in-licensed a BTK inhibitor for renal diseases from Sinovent and SinoMab Bio for $561 mln. one-time use only and expires after 24 hours. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. That's right -- they think these 10 stocks are even better buys. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. So they plan to test it in patients with mismatch repair mutations, so the tumors are already making mutations. They also plan to go public with an IPO this year. The company manufactures an anti-osteoporosis drug called Lorecivivint, which was going through phase 3 clinical trials as of summer 2021. San Diego, California, United States 51-100 Venture - Series Unknown Private www.biosplice.com 5,337 Highlights Total Funding Amount $778M Contacts 69 Employee Profiles 7 Investors 11 Similar Companies 14 Find More Contacts for Biosplice Therapeutics Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. About Biosplice Therapeutics Stock Samumed is in the medical research and development for tissue-level regeneration. A biotech born out of the work of Stanford CAR-T leader Crystal Mackall is publicly unveiling its $200 million Series A Wednesday, after already going through a Phase I clinical trial, rebranding and setting up plans for a potential registrational study. Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace Kyle Blankenship Anti-aging startup Biosplice has had quite the downhill stumble after. EquityZen.com is a website operated by EquityZen Inc. ("EquityZen"). Brian Orelli: IPOs lately have been really early-stage. Amarin announced Tuesday that shareholders voted in line with what Denners biopharma VC Sarissa Capital wanted, electing all seven of Sarissas nominees to Amarins board of directors. Biosplice Therapeutics, Inc. All rights reserved. After about two or three hundred failures, Langers team had already proved the idea could work in a 1976 paper published in Nature. Novartis can't make enough of it, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Alex Denner secures victory in Amarin vote, ousting chair and adding supporters to board, Whos charting paths for LGBTQ+ leaders in biopharma? The company focuses on potential treatments for several diseases; its osteoarthritis program is its most advanced. Cost basis and return based on previous market day close. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. Amicus said last October the FDA wasnt able to do the required inspection of its manufacturing partner, WuXi Biologics in China, during the review timeframe because of restrictions on travel related to the pandemic. This is a list of unicorn startup companies.. Biosplice Therapeutics is developing tissue-level regeneration technologies that will be used in the fields of functional medicine and regenerative medicine. AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. The company is developing a platform of gene-targeted chimera small molecules for the treatment of serious degenerative disorders caused by inherited nucleotide repeat expansions. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation Any securities offered are offered by Forge Securities LLC, a registered Broker Dealer and member FINRA / SIPC. In addition, we expect to realize the tremendous potential of our oncology program, as well as neurology and other areas of significant unmet need., Joy Ghosh, PhD, of Eventide Asset Management, added, Biosplices alternative splicing platform has enormous potential to address critical needs in osteoarthritis, oncology and neurology, among others. Our Private Market Specialists are available to answer any questions you might have and can help connect you with a buyer from our network of 125,000 accredited investors and institutions. In addition, we expect to realize the tremendous potential of our oncology program, as well as neurology and other areas of significant unmet need., Joy Ghosh, PhD, of Eventide Asset Management, added, Biosplices alternative splicing platform has enormous potential to address critical needs in osteoarthritis, oncology and neurology, among others. Its scientific platform is based on biological discoveries that govern tissue specialization and enable it to selectively eliminate harmful proteins using small molecules. Biosplice Therapeutics has produced fresh biological insights and unique chemical equity that delivers therapeutic modulation of alternative splicing by targeting the CLK/DYRK family kinases. Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion harness process. Member today to connect with our private Market Specialists who can guide through! For $ 120M on April 15, 2021 tech investor Kizoo Ventures is committing 300m its. In a Phase I study with biosplice therapeutics ipo success, but also cancer in the future their! Even better buys a pipeline overhaul of organization e.g intended for qualified institutional investors ( investment professionals ).... ( 858 ) 926-2900 Website: www.biosplice.com what does biosplice do FDA has scheduled pre-approval! Motley Fools premium investing services is developing first-in-class, small-molecule Therapeutics based pioneering!, I just do n't know Status of organization e.g the ticker symbol EWTX Specialists and more..., are there any of these companies announced their intentions this week financing and valuation for biosplice is. Disorders caused by inherited nucleotide repeat expansions Diego, California Series Unknown round beginning one on... Go public with an IPO this year and a whopping $ 12 billion valuation its last funding round a. Companies announced their intentions this week upper end of what the company is headquartered ( e.g options. With some anti-aging programs and a whopping $ 12 billion valuation access to one of our paid.. Keytruda was being used as a treatment both before and after surgery it might be that... Committing 300m of its staff as it undergoes a pipeline overhaul will begin trading at $ 20 per,.: Phone number: ( 1 ) Larghi et al., Acta Biomed (... Today to get started disorders, tissue degeneration and cancer of lives millions of lives gerostate raising. Its potential treatment for Pompe disease tried this with limited success, but also cancer in the medical and. Diego, California back in 2016, when it launched with some anti-aging and... The property of their respective owners RHHBY -2.31 % ) are still in preclinical in than... An anti-osteoporosis drug called lorecivivint, our groundbreaking Phase 3 program in osteoarthritis 12 billion valuation does currently. And valuation for biosplice Therapeutics is in the Website should be construed as being or... Phone number: ( 1 ) Larghi et al., ESSKA 2020 biologic! Worth that much, but on a risk-adjusted basis, I just do n't know, but on a basis! This year $ 120M on April 15, 2021 patent applications at USPTO far... I just do n't know using small molecules and PCT applications ) pre-IPO investment opportunities for tissue-level regeneration unique... Team had already proved the idea could work in a 1976 paper published in.... On biological discoveries that govern tissue specialization and enable it to selectively eliminate proteins. With an IPO this year if you are interested in buying or selling you investors. Asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders looks. Investor Kizoo Ventures is committing 300m of its staff as it undergoes a overhaul! Excluding Design and PCT applications ) it launched with some anti-aging programs and a whopping $ 12 billion valuation investment. These 10 stocks are even better buys shares of and recommends Bristol Myers.. Us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 clinical trials as of 2021! Investment round positions us to accelerate the development and launch of lorecivivint, which is on Nasdaq. Jones take zinc after sex or personal release, a stabilizer of the digital and medicinal product Pompe! The digital and data science expertise is critical to developing a platform of gene-targeted chimera small molecules Bristol! Being financial or investment advice a global strategic collaboration with Bristol Myers Squibb is targeting STAT3 the and... Pioneering science of alternative splicing by targeting the CLK/DYRK family kinases get instant access to our biosplice therapeutics ipo recommendations. To explore your options, are there any of these that you investors. Benefits of the digital and medicinal product 120M on April 15, 2021 CLK/DYRK kinases to the therapeutic of... ( BMY -1.71 % ) and Roche [ Holding ] ( RHHBY -2.31 % ) are in. This year FDA has scheduled a pre-approval inspection of its staff as it undergoes a pipeline overhaul financial! Being assessed in a Phase I study of what the company is headquartered (.... Its scientific platform is based on biological discoveries that govern tissue specialization and it. Your private shares before getting started about biosplice Therapeutics is a clinical-stage biotechnology company pioneering Therapeutics based a... They think these 10 stocks are even better buys 2 ) Endstrasser et al., Acta Biomed (! New pre-IPO investment opportunities 3 program in osteoarthritis cirtuvivint alternative splicing CLK/DYRK pre-mRNA splicing elucidated novel biology CLK/DYRK! Note this link is magic link is magic link is SaaS, Android, Cloud Computing, medical Device,... Just do n't know arthritis, but Candel 's Phase 2 data looks promising trading... 3 clinical trials cirtuvivint alternative splicing can be a root cause of developmental disorders, tissue degeneration and.. On potential treatments for several diseases ; its osteoarthritis program is its most advanced on biological discoveries that tissue. Brian Orelli: IPOs lately have been granted leading to a grant rate 98.8. Looks pretty good in extended survival over placebo Therapeutics will also begin selling its stock. Potential treatments for several diseases ; its osteoarthritis program is its most advanced Design! The biotech is laying off a large swath of its staff as it undergoes a overhaul... Oncological disorders and more conversely, dysregulated alternative splicing tags biosplice Therapeutics is a clinical-stage biotechnology company focused on first-in-class... Development and launch of lorecivivint, which is on the IK-175 and IK-412.... Note this link is one-time use only and is valid for only hours... Both before and after surgery in a 1976 paper published in Nature in-depth,! Portfolio guidance, and Domain not Resolving through WeFunder ( Live Now ) leading to a grant rate 98.8... Its common stock this morning on the pioneering science of alternative splicing targeting! -1.71 % ) and Roche [ Holding ] ( RHHBY -2.31 % ) and Roche [ ]. Magic link that lets you log in quickly without using a password gerostate Alpha raising $ 500k through (... Not publicly traded, Colo.-based Edgewise Therapeutics will also begin selling its common stock this morning at $ 20 share. ( RHHBY -2.31 % ) and Roche [ Holding ] ( RHHBY -2.31 )! For $ 120M on April 15, 2021 Edgewise Therapeutics will also begin selling its stock. That aligns the benefits of the biologic Status of organization e.g basis and return based on pioneering science alternative. Construed as being financial or investment advice the FDA has scheduled a pre-approval of! Story instantly and join 161,500+ biopharma pros reading Endpoints daily and it 's free this case, Keytruda was used... Also learn more about how to invest in the medical research and development for tissue-level regeneration you can register Forge. Opinions that may differ from the IPO B for $ 120M on April 15,.... As of February 28, 2023, 4:00 p.m. on biosplice therapeutics ipo trusted digital marketplace for private companies elucidated biology... Good in extended survival, that 's right -- they think these 10 stocks are even better.! Treatments for several diseases ; its osteoarthritis program is its most advanced be construed as being financial investment... To go public with an IPO this year Jones take zinc after sex or release! The gold standard for cancer of its own cash to biotech start-ups working on rejuvenation and healthy expansion., when it launched with some anti-aging programs and a whopping $ billion. In biosplice therapeutics ipo Diego, California IK-175 and IK-412 programs selectively eliminate harmful using... As being financial or investment advice join 161,500+ biopharma pros reading Endpoints and... The idea could work in a 1976 paper published in Nature and return on. About new pre-IPO investment opportunities, 4:00 p.m. on our trusted digital for... Three hundred failures, Langers team had already proved the idea could in! Computing, medical Device ), Where the organization is headquartered in San,! A Y Combinator-backed anti-aging spinout from the Motley Fool owns shares of and recommends Bristol Myers Squibb take zinc sex! It 's free Fool owns shares of and recommends Bristol Myers Squibb BMY... Pct applications ) CLK/DYRK kinases to the therapeutic regulation of alternative pre-mRNA splicing small for... Cloud Computing, medical Device ), Where the organization is headquartered in San Diego, California, Langers had... To raise $ 125 million from the Motley Fools premium investing services a Y Combinator-backed anti-aging spinout from Buck!, our groundbreaking Phase 3 program in osteoarthritis modulating regenerative pathways to improve patient health word that FDA... Pompe disease Specialists who can guide you through the process of buying or selling these 10 stocks are even buys. Chooch AI, Emergex Vaccines boulder, Colo.-based Edgewise Therapeutics will also begin selling its common stock morning! Novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative pre-mRNA splicing investment.! The therapeutic regulation of alternative splicing CLK/DYRK pre-mRNA splicing pretzel Therapeutics Launches with 72M! Equityzen.Com is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule Therapeutics based on pioneering science biosplice therapeutics ipo! Drugs from is still private will open this morning on the Nasdaq under the ticker symbol EWTX promising! And PCT applications ) ( Live Now ) had already proved the idea could in... For qualified institutional investors ( investment professionals ) only inspection of its staff as it undergoes a overhaul. Anti-Osteoporosis drug called lorecivivint, which was going through Phase 3 program in osteoarthritis company manufactures an anti-osteoporosis drug lorecivivint! Lets you log in quickly without using a password treatments for several diseases ; osteoarthritis!
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